A Novel Nuclear Function for the Interleukin-17 Signaling Adaptor Protein Act1
نویسندگان
چکیده
منابع مشابه
A Novel Nuclear Function for the Interleukin-17 Signaling Adaptor Protein Act1
In the context of the human airway, interleukin-17A (IL-17A) signaling is associated with severe inflammation, as well as protection against pathogenic infection, particularly at mucosal surfaces such as the airway. The intracellular molecule Act1 has been demonstrated to be an essential mediator of IL-17A signaling. In the cytoplasm, it serves as an adaptor protein, binding to both the intrace...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0163323